.University of Milano  Department of Biomolecular Sciences and Biotechnology  
 
 
 

head of the group: Prof. Martino Bolognesi

 

 

 

 


 


PUBLICATIONS 

2008/09     2007     2006     2005     2004     2003     before

Bollati, M., Milani, M., Mastrangelo, E., de Lamballerie, X., Canard, B. & Bolognesi, M.  
Crystal structure of a methyltransferase from a no-known-vector Flavivirus.
Biochem. Biophys. Res. Commun. (2009) 382, 200-204 [PubMed].
Milani, M., Mastrangelo, E., Bollati, M., Selisko, B., Decroly, E., Bouvet, M., Canard, B. & Bolognesi, M.
Flaviviral methyltransferase/RNA interaction: Structural basis for enzyme inhibition.
Antiviral Res. (2009) 83, 28–34 [PubMed]
Nardini, M., Valente, C., Ricagno, S., Luini, A., Corda, D. & Bolognesi, M.
CtBP1/BARS Gly172
-Glu mutant structure: Impairing NAD(H)-binding.
Biochem. Biophys. Res. Commun. (2009), 381, 70-74 
[PubMed]
Cossu, F., Mastrangelo, E., Milani, M., Sorrentino, G., Lecis, D., Delia, D., Manzoni, L., Seneci, P., Scolastico, C. & Bolognesi. M.
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2.

Biochem. Biophys. Res. Commun. (2009) 378, 162-167 [PubMed].
Bollati, M.. Milani, M., Mastrangelo, E., Ricagno, S., Tedeschi, G., Nonnis, S., Decroly, E., Selisko, B., de Lamballerie, X., Coutard, B., Canard, B., Bolognesi, M.
Recognition of the RNA cap in Wesselsbron virus NS5 methyltransferase domain: implications for RNA capping mechanisms in Flavivirus.
J.
Mol. Biol. (2009) 385, 140-152 [PubMed].
Bolognesi, M. and Smith, J. L.
Proteins: ever larger, stranger and more dynamic.
Curr. Opin. Struct. Biol
. (2008) 18, 690-692.
[PubMed].
Ascenzi, P., Bocedi, A., Heptonstall, J., Capobianchi, M.R., Di Caro, A., Mastrangelo, E., Bolognesi, M., Ippolito, G.
Ebolavirus and Marburgvirus: insight the Filoviridae family.

Mol. Aspects Med. (2008) 29,151-185 [PubMed].

Nardini, M., Pesce, A., Thijs, L., Saito, J.A., Dewilde, S., Alam, M., Ascenzi, P., Coletta, M., Ciaccio, C., Moens, L., and Bolognesi, M. 
Archaeal protoglobin structure suggests novel ligand diffusion paths and heme-reactivity modulation. 
EMBO Reports 
(2008) 9, 157-163 [PubMed].

Boechi, L., Martí, M.A., Milani, M., Bolognesi, M., Luque, F.J., Estrin, D.A.
Structural determinants of ligand migration in Mycobacterium tuberculosis truncated hemoglobin O.
Proteins: Structure, Function, and Bioinformatics  (2008) 73, 372-379 [PubMed].
Dewilde, S., Ioanitescu, I.A., Kiger, L., Gilany, K., Marden, M.C., Van Doorslaer, S., Vercruysse, J., Pesce, A., Nardini, M., Bolognesi, M., Moens, L. 
The hemoglobins of the trematodes Fasciola hepatica 
and Paramphistomum epiclitum. A molecular biological, physico-chemical, kinetic and vaccination study.
Protein Science
(2008)
17, 1653-1662 [PubMed].
Mastrangelo, E., Cossu, F., Milani, M., Sorrentino, G., Lecis, D., Delia, D., Manzoni, L., Drago, C., Seneci, P., Scolastico, C., Rizzo, V., Bolognesi, M
Targeting the X-linked inhibitor of apoptosis protein through azabicyclo[5.3.0]alkane smac mimetics. 4-substituted.  Structure, activity, and recognition principles. 
J.
Mol. Biol. (2008) 384, 673-689 [PubMed].
Pesce, A., Thijs, L., Nardini,M., Desmet, F., Sisinni, L., Gourlay, L., Bolli, A., Coletta, M., Van Doorslaer, S., Wan, X., Alam, M., Ascenzi, P., Moens, L., Bolognesi, M., Dewilde, S.
HisE11 and HisF8 provide bis-histidyl heme hexa-coordination in the globin domain of Geobacter sulfurreducens Globin-Coupled Sensor
J. Mol. Biol. (2009) 386, 246-260 [PubMed].
Salter, M.D., Nienhaus, K., Nienhaus, G.U., Dewilde, S., Moens, L., Pesce, A., Nardini, M., Bolognesi, M., Olson, J.S.
The apolar channel in Cerebratulus lacteus hemoglobin is the route for O2 entry and exit

J. Biol. Chem. (2008) 283, 35689-35702 [PubMed].
Ouellet, Y.H., Daigle, R., Lagüe, P., Dantsker, D., Milani, M., Bolognesi, M., Friedman, J.M., Guertin, M.
Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water.
J. Biol. Chem. (2008) 283, 27270-27278
[PubMed].
Pesce, A., Milani, M., Nardini, M. and Bolognesi, M. 
Mapping heme-ligand tunnel in group I truncated(2/2) hemoglobins. 
Methods Enzymol. (2008) 436C, 303-315
[PubMed].
Labarre, M., Pesce, A., Couture, M., Nardini, M., Bolognesi, M., Wittenberg, J.B, Wittenberg, B.A, and Guertin, M.  
Spectroscopic, kinetic and structural characterization of a group II truncated hemoglobin from the plant pathogen Agrobacterium tumefaciens
Protein Science.
(2008) Submitted.
Occhino, M., Ghiotto, F., Soro, S., Mortasino, M., Bosi, S., Maffei, M., Bruno, S., Nardini, M., Figini, M., Tramontano, A. and Ciccone, E.  
Dissecting the structural determinants of the interaction between the HCMV UL18 protein and the CD85j immune receptor. 

J. of Immunology
(2008) 180
, 957-968 [PubMed]
Nadra, A.D., Martí, M.A., Pesce, A., Bolognesi, M. and Estrin, D.A.
Exploring the molecular basis of heme coordination in human neuroglobin
Proteins: Structure, Function, and Bioinformatics
(2008) 71, 695-705 [PubMed].
Esposito, G., Ricagno, S., Corazza, A., Rennella, E., Gümral, D., Mimmi, M.C., Betto, E., Pucillo, C.E., Fogolari, F., Viglino, P., Raimondi, S., Giorgetti, S., Bolognesi, B., Merlini, G., Stoppini, M., Bolognesi, M., Bellotti, V.
The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties.
J. Mol. Biol. (2008) 378885-895
[PubMed].
Ricagno, S., Colombo, M., Rosa, M.D., Sangiovanni, E., Giorgetti, S., Raimondi, S., Bellotti, V., Bolognesi, M.
DE loop mutations affect beta2-microglobulin stability and amyloid aggregation.
Biochem. Biophys. Res. Commun. (2008) 
377, 146-150 [PubMed].
Milani, M., Nardini, M., Pesce, A., Mastrangelo, E., Bolognesi, M.
Hemoprotein time-resolved X-ray crystallography.
IUBMB Life (2008) 60, 154-158 [PubMed].
Bolli, A., Ciaccio, C., Coletta, M., Nardini, M., Bolognesi, M., Pesce, A., Guertin, M., Visca, P. and Ascenzi, P. Ferrous Campylobacter jejuni truncated hemoglobin P displays an extremely high reactivity for cyanide. 
FEBS J. (2008)  275, 303-315 [PubMed].
Coutard, B., Gorbalenya, A. E., Snijder, E. J., Leontovich, A. M., Poupon, A., De Lamballerie, X., Charrel, R., Gould, E. A., Gunther, S., Norder, H., Klempa, B., Bourhy, H., Rohayem, J., L'Hermite, E., Nordlund, P., Stuart, D. I., Owens, R. J., Grimes, J. M., Tucker, P. A., Bolognesi, M., Mattevi, A., Coll, M., Jones, T. A., Aqvist, J., Unge, T., Hilgenfeld, R., Bricogne, G., Neyts, J., La Colla, P., Puerstinger, G., Gonzalez, J. P., Leroy, E., Cambillau, C., Romette, J. L. and Canard, B.
The VIZIER project: preparedness against pathogenic RNA viruses.

Antiviral Res.
(2008) 78, 37-46
[PubMed].
Spallarossa, A., Cesarini, S., Ranise, A., Ponassi, M., Unge, T., Bolognesi, M.
Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors.
Biochem. Biophys. Res. Commun. (2008) 365,764-770 [PubMed].

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