2015

 

Decoding the Structural Bases of D76N ß2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis. de Rosa M, Barbiroli A, Giorgetti S, Mangione PP, Bolognesi M, Ricagno S. PLoS One. 2015 Dec 1;10(12):e0144061. doi: 10.1371/journal.pone.0144061

 

A redox signalling globin is essential for reproduction in Caenorhabditis elegans. De Henau S, Tilleman L, Vangheel M, Luyckx E, Trashin S, Pauwels M, Germani F, Vlaeminck C, Vanfleteren JR, Bert W, Pesce A, Nardini M, Bolognesi M, De Wael K, Moens L, Dewilde S, Braeckman BP. Nat Commun. 2015 Dec 1;6:8782. doi: 10.1038/ncomms9782.

 

Selecting soluble/foldable protein domains through single-gene or genomic ORF filtering: structure of the head domain of Burkholderia pseudomallei antigen BPSL2063. Gourlay LJ, Peano C, Deantonio C, Perletti L, Pietrelli A, Villa R, Matterazzo E, Lassaux P, Santoro C, Puccio S, Sblattero D, Bolognesi M. Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2227-35. doi: 10.1107/S1399004715015680.

 

A covalent homodimer probing early oligomers along amyloid aggregation. Halabelian L, Relini A, Barbiroli A, Penco A, Bolognesi M, Ricagno S.Sci Rep. 2015 Sep 30;5:14651. doi: 10.1038/srep14651.

 

Structural Biology of Bacterial Haemophores. Ascenzi P, di Masi A, Leboffe L, Frangipani E, Nardini M, Verde C, Visca P. Adv Microb Physiol. 2015;67:127-76. doi: 10.1016/bs.ampbs.2015.09.002.

 

Sequence- and Structure-Based Immunoreactive Epitope Discovery for Burkholderia pseudomallei Flagellin. Nithichanon A, Rinchai D, Gori A, Lassaux P, Peri C, Conchillio-Solé O, Ferrer-Navarro M, Gourlay LJ, Nardini M, Vila J, Daura X, Colombo G, Bolognesi M, Lertmemonkolchai G. PLoS Negl Trop Dis. 2015 Jul 29;9(7):e0003917. doi: 10.1371/journal.pntd.0003917

 

Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans. Tilleman L, Abbruzzetti S, Ciaccio C, De Sanctis G, Nardini M, Pesce A, Desmet F, Moens L, Van Doorslaer S, Bruno S, Bolognesi M, Ascenzi P, Coletta M, Viappiani C, Dewilde S. PLoS One. 2015 Jun 5;10(6):e0125959. doi: 10.1371/journal.pone.0125959.

 

Structural flexibility of the heme cavity in the cold-adapted truncated hemoglobin from the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125. Giordano D, Pesce A, Boechi L, Bustamante JP, Caldelli E, Howes BD, Riccio A, di Prisco G, Nardini M, Estrin D, Smulevich G, Bolognesi M, Verde C. FEBS J. 2015 Aug;282(15):2948-65. doi: 10.1111/febs.13335.

 

Backbone and side-chain (1)H, (15)N, (13)C assignment and secondary structure of BPSL1445 from Burkholderia pseudomallei. Quilici G, Berardi A, Gaudesi D, Gourlay LJ, Bolognesi M, Musco G. Biomol NMR Assign. 2015 Oct;9(2):347-50. doi: 10.1007/s12104-015-9607-1.

 

Wild type beta-2 microglobulin and DE loop mutants display a common fibrillar architecture. Natalello A, Relini A, Penco A, Halabelian L, Bolognesi M, Doglia SM, Ricagno S. PLoS One. 2015 Mar 24;10(3):e0122449. doi: 10.1371/journal.pone.0122449.

 

Crystal structure of LptH, the periplasmic component of the lipopolysaccharide transport machinery from Pseudomonas aeruginosa. Bollati M, Villa R, Gourlay LJ, Benedet M, Dehò G, Polissi A, Barbiroli A, Martorana AM, Sperandeo P, Bolognesi M, Nardini M.FEBS J. 2015 May;282(10):1980-97. doi: 10.1111/febs.13254.

 

The activator of apoptosis Smac-DIABLO acts as a tetramer in solution. Mastrangelo E, Vachette P, Cossu F, Malvezzi F, Bolognesi M, Milani M. Biophys J. 2015 Feb 3;108(3):714-23. doi: 10.1016/j.bpj.2014.11.3471.

 

From crystal structure to in silico epitope discovery in the Burkholderia pseudomallei flagellar hook-associated protein FlgK. Gourlay LJ, Thomas RJ, Peri C, Conchillo-Solé O, Ferrer-Navarro M, Nithichanon A, Vila J, Daura X, Lertmemongkolchai G, Titball R, Colombo G, Bolognesi M. FEBS J. 2015 Apr;282(7):1319-33. doi: 10.1111/febs.13223.

 

NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathway. Cossu F, Milani M, Grassi S, Malvezzi F, Corti A, Bolognesi M, Mastrangelo E. Proteins. 2015 Apr;83(4):612-20. doi: 10.1002/prot.24766

 

Functional and dysfunctional conformers of human neuroserpin characterized by optical spectroscopies and Molecular Dynamics. Noto R, Santangelo MG, Levantino M, Cupane A, Mangione MR, Parisi D, Ricagno S, Bolognesi M, Manno M, Martorana V. Biochim Biophys Acta. 2015 Feb;1854(2):110-7. doi: 10.1016/j.bbapap.2014.10.002.

 

TREX1 C-terminal frameshift mutations in the systemic variant of retinal vasculopathy with cerebral leukodystrophy. DiFrancesco JC, Novara F, Zuffardi O, Forlino A, Gioia R, Cossu F, Bolognesi M, Andreoni S, Saracchi E, Frigeni B, Stellato T, Tolnay M, Winkler DT, Remida P, Isimbaldi G, Ferrarese C. Neurol Sci. 2015 Feb;36(2):323-30. doi: 10.1007/s10072-014-1944-9.

 

Rapid proton-detected NMR assignment for proteins with fast magic angle spinning. Barbet-Massin E, Pell AJ, Retel JS, Andreas LB, Jaudzems K, Franks WT, Nieuwkoop AJ, Hiller M, Higman V, Guerry P, Bertarello A, Knight MJ, Felletti M, Le Marchand T, Kotelovica S, Akopjana I, Tars K, Stoppini M, Bellotti V, Bolognesi M, Ricagno S, Chou JJ, Griffin RG, Oschkinat H, Lesage A, Emsley L, Herrmann T, Pintacuda G. J Am Chem Soc. 2014 Sep 3;136(35):12489-97. doi: 10.1021/ja507382j.

 

 

 

 

 

 

Publications

Last update 07/12/19

The Structural Biology Group comprises members from both the DBS-UNIMI and the IBF-CNR. The content herein is not regulated by the University of Milan.